Basic Information

IDDRAMP21252
SequenceFLFSLIPSAIAGLVSAIRN
Length19
NameAaeAP2 (Scorpionida, Arachricla, Arthropoda)
SourceAndroctonus aeneas
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=16 mg/L, MBC=16 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>512 mg/L);##Fungi : Candida albicans(MIC=32 mg/L, MBC=64 mg/L)
Hemolytic Activity[Ref.25626077] 100% hemolysis at 64 μg/ml against horse red blood cells
Cytotoxicity[Ref.25626077] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot A0A060QMQ0 
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25626077

Physicochemical Properties

Residues19
SequenceFLFSLIPSAIAGLVSAIRN
Molecular Weight1989.36
Grand Average of Hydropathy1.458
Isoelectric Point9.75
Charge at pH 7.40.557
Secondary StructureHelix: 0.474, Turn: 0.316, Sheet: 0.316
Instability Index24.589
Aromaticity0.105

Similar Structure Search

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