Basic Information

IDDRAMP21403
SequenceITEVITILLNRLTDRLEK
Length18
Namepeptide 1 (De Novo Synthesis)
Sourcesynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.31117348] Gram-positive bacteria:Staphylococcus aureus ATCC 6538(MIC>100μM), Bacillus subtilis ATCC 6633(MIC>100μM);##Gram-negative bacteria:Escherichia coli ATCC 15597(MIC>100μM), Pseudomonas aeruginosa (MIC>100μM), Salmonella Typhimurium 6192(MIC>100μM), Klebsiella pneumoniae NCTC 5055(MIC>100μM)
Hemolytic Activity[Ref.31117348] 5% hemolysis at 250 μM against human blood cells.
Cytotoxicity[Ref.31117348] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID31117348

Physicochemical Properties

Residues18
SequenceITEVITILLNRLTDRLEK
Molecular Weight2140.523
Grand Average of Hydropathy0.217
Isoelectric Point6.182
Charge at pH 7.4-0.442
Secondary StructureHelix: 0.444, Turn: 0.056, Sheet: 0.333
Instability Index26.656
Aromaticity0

Similar Structure Search

Candidates based on structure

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