Basic Information

IDDRAMP29124
SequenceLNLKKLLKVAKKIL
Length14
NameMastoparan-C [A5,8K]
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=16 µM); Bacillus subtilis ATCC 23857(MIC=4 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=8 µM); Pseudomonas aeruginosa ATCC 9027(MIC=4 µM); Klebsiella pneumoniae ATCC 700603(MIC=8 µM).
Hemolytic Activity[Ref.33285267]15% hemolysis against mouse erythrocytes at 256 µM.
Cytotoxicity[Ref.33285267]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01516
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33285267

Physicochemical Properties

Residues14
SequenceLNLKKLLKVAKKIL
Molecular Weight1622.134
Grand Average of Hydropathy0.464
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.500, Turn: 0.071, Sheet: 0.429
Instability Index-7.279
Aromaticity0

Similar Structure Search

Candidates based on structure

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