Basic Information

IDDRAMP29125
SequenceLNLKALLAVAKKI
Length13
NameMastoparan-C (1-13)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=64 µM); Bacillus subtilis ATCC 23857(MIC=16 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=16 µM); Pseudomonas aeruginosa ATCC 9027(MIC=32 µM); Klebsiella pneumoniae ATCC 700603(MIC=64 µM).
Hemolytic Activity[Ref.33285267]0% hemolysis against mouse erythrocytes at 256 µM.
Cytotoxicity[Ref.33285267]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01516
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33285267

Physicochemical Properties

Residues13
SequenceLNLKALLAVAKKI
Molecular Weight1394.787
Grand Average of Hydropathy1.085
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.462, Turn: 0.077, Sheet: 0.538
Instability Index-3.831
Aromaticity0

Similar Structure Search

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