Basic Information

IDDRAMP29145
SequenceGGLIGTLTAKQIKK
Length14
NamePxt-7
SourceXenopus tropicalis
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.25312021]Gram-negative bacteria:Escherichia coli DH5α(Not active up to 150 µg/ml);##Gram-positive bacteria:Staphylococcus aureus JCM 2151(Not active up to 150 µg/ml).
Hemolytic Activity[Ref.25312021]0.4% Hemolysis against Rat erythrocytes at 20 µM.
Cytotoxicity[Ref.25312021]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25312021

Physicochemical Properties

Residues14
SequenceGGLIGTLTAKQIKK
Molecular Weight1427.731
Grand Average of Hydropathy0.043
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.286, Turn: 0.214, Sheet: 0.214
Instability Index22.857
Aromaticity0

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