Basic Information

IDdbAMP05846
SequenceLLGMIPLAISAISALSKL
Length18
NamePhylloseptin-L1data about MIC or HC50 is present&&Phylloseptin-L1&&Phyllin-AC, Phylloseptin-L1, Medusin-AC&&Medusin-AC&&Hylomantis lemur (Hylidae: Phyllomedusinae
SourceHylomantis lemur (Hylidae: Phyllomedusinae
ActivityAntibacterial
PathogenStaphylococcus aureus NCTC 10788 (MIC=8µg/ml)&&Staphylococcus aureus ATCC 25923 (MIC=8µM)&&RBCs Source of Human (LC50 =40µM)&&RBCs Source of Horse (8.7% hemolysis at 32mg/ml)&&Human hepatocellular carcinoma HepG2 (LC50=35µM)&&Escherichia coli NCTC 10418 &
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23415652, 17561225, 17561225

Physicochemical Properties

Residues18
SequenceLLGMIPLAISAISALSKL
Molecular Weight1811.276
Grand Average of Hydropathy1.75
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.444, Turn: 0.278, Sheet: 0.500
Instability Index3.128
Aromaticity0

Similar Structure Search

Candidates based on structure

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