Basic Information

IDDRAMP01888
SequenceFFPTIAGLTKLFCAITKKC
Length19
NameBrevinin-1CHc (Frogs, amphibians, animals)
SourceRana chiricahuensis
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: E. coli (MIC=80 µM);##Gram-positive bacterium: S. aureus (MIC=20 µM).##Yeast: C. albicans (MIC=20 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys13 and Cys19)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21262304

Physicochemical Properties

Residues19
SequenceFFPTIAGLTKLFCAITKKC
Molecular Weight2102.604
Grand Average of Hydropathy0.937
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.368, Turn: 0.105, Sheet: 0.211
Instability Index15.142
Aromaticity0.158

Similar Structure Search

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