Basic Information

IDdbAMP09485
SequenceMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
Length40
NameMacaca mulatta (Rhesus macaque)&&Liver-expressed antimicrobial peptide 2, LEAP-2&&Liver-expressed antimicrobial peptide 2 Linear, LEAP-2 Linear&&Liver-expressed antimicrobial peptide 2 (LEAP-2; primates, mammals, animals)&&LEAP2_HUMAN&&Homo sapiens
SourceMacaca mulatta (Rhesus macaque)&&Homo sapiens
ActivityAntibacterial
PathogenMicrococcus luteus ATCC 9341 (MIC=>200µM)&&Micrococcus luteus ATCC 9341 (MIC=100µM)&&Escherichia coli ATCC 25922 (MIC=>200µM)&&Bacillus subtilis ATCC 6051 (MIC=>200µM)&&Bacillus megaterium ATCC 14581 (MIC=200µM)&&Bacillus megaterium ATCC 14581 (MIC=12.5µM
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q969E1&&Q91V13&&Q95M25&&Q969E1&&Q969E1&&Q95M25
PDB 2L1Q
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20845358, 15489334, 12493837, 12493837

Physicochemical Properties

Residues40
SequenceMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
Molecular Weight4585.304
Grand Average of Hydropathy-0.402
Isoelectric Point9.367
Charge at pH 7.43.189
Secondary StructureHelix: 0.225, Turn: 0.225, Sheet: 0.200
Instability Index75.28
Aromaticity0.05

Similar Structure Search

Candidates based on structure

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