| ID | dbAMP11739 |
|---|---|
| Sequence | VGALAVVVWLWLWLW |
| Length | 15 |
| Name | Synthetic&&Sequence 11 from patent US 7078380&&MPA-Gramicidin A-MEA&&MPA-Gramicidin A&&Gramicidin A (GA; Nonribosomally synthesized bacteriocin)&&Gramicidin A&&Bacillus brevis (soil bacterium) (Gram-positive bacteria)&&Act-Gramicidin A-MEA&&Act-Gramicidin |
| Source | Synthetic&&Bacillus brevis (soil bacterium) (Gram-positive bacteria) |
| Activity | Antibacterial |
| Pathogen | Streptococcus pyogenes ATCC 19615 (MIC=0.16µM)&&Streptococcus pneumoniae (MIC=>64µg/ml)&&Streptococcus pneumoniae (MIC=0.05µg/ml)&&Staphylococcus epidermidis PP62A (MIC=>64µg/ml)&&Staphylococcus epidermidis PP62A (MIC=1µg/ml)&&Staphylococcus epidermidis P |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | 1MAG&&1GRM |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19870884, 8810522 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | VGALAVVVWLWLWLW |
| Molecular Weight | 1811.216 |
| Grand Average of Hydropathy | 2.107 |
| Isoelectric Point | 5.495 |
| Charge at pH 7.4 | -0.477 |
| Secondary Structure | Helix: 0.800, Turn: 0.067, Sheet: 0.400 |
| Instability Index | 70.053 |
| Aromaticity | 0.267 |