| ID | dbAMP22949 |
|---|---|
| Sequence | GWGSFFKKAAAVGKAVGKAALTAYL |
| Length | 25 |
| Name | [A11,15,23]Ple&&Pleurocidin [H11A][H15A][H23A] |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus IFO 12732 (MIC=16µg/ml)&&RBCs Source of Rabbit (15% hemolysis at 100µM)&&RBCs Source of Human (45% hemolysis at 100µM)&&Pseudomonas aeruginosa IFO 12582 (MIC=16µg/ml)&&Escherichia coli IFO 12734 (MIC=16µg/ml)&&Bacillus subtilis IFO 3 |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11168895, 11168895 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | GWGSFFKKAAAVGKAVGKAALTAYL |
| Molecular Weight | 2512.944 |
| Grand Average of Hydropathy | 0.532 |
| Isoelectric Point | 10.177 |
| Charge at pH 7.4 | 3.545 |
| Secondary Structure | Helix: 0.320, Turn: 0.200, Sheet: 0.360 |
| Instability Index | -9.208 |
| Aromaticity | 0.16 |