Basic Information
| ID | DRAMP01257 |
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| Sequence | GLWSKIKAAGKEAAKAAAKAAGKAALNAVSEAV |
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| Length | 33 |
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| Name | Dermadistinctin-K (DD K; Frogs, amphibians, animals) |
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| Source | Phyllomedusa distincta (Monkey frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus (MIC=4.7 µM), Enterococcus faecalis (MIC>19 µM);Gram-negative bacteria: Pseudomonas aeruginosa (MIC=2.4 µM), Escherichia coli (MIC=0.6 µM).##Fungi: Candida tropicalis (MIC=10.1 µM), Candida guilliermondii (MIC=20.3 µM), Candida albicans (MIC=20.3 µM), Candida albicans ATCC 1023 (MIC=10.1 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.10477123]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P83638 |
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| PDB |
2K9B, 2JX6 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10477123 |
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