Basic Information
| ID | DRAMP01646 |
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| Sequence | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV |
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| Length | 33 |
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| Name | Adenoregulin (Dermaseptin BII; Dermaseptin B2; Frogs, amphibians, animals) |
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| Source | Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.8306981]Fungi: Microsporum canis (IP 1194) (MIC=10 µg/ml), Tricophyton rubrum (IP 1400-82) (MIC=15 µg/ml), Arthroderma simii (IP 1063-74) (MIC=30 µg/ml), Aspergillus fumigatus IP (1025-70) (MIC=125 µg/ml), Aerornonas caviae (IP 67-16 T) (MIC=60 µg/ml), Cryptococcus neoformans (IP 960-67) (MIC=15 µg/ml), Cryptococcus neoformans (IP 962-67) (MIC=15 µg/ml), Candida albicans (IP 884-65) (MIC=15 µg/ml);##Gram-negative bacterium: Escherichia coli (IP 76-24) (MIC=15 µg/ml);##Gram-positive bacterium: Nocardia brasiliensis (IP 16-80) (MIC=30 µg/ml). |
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| Hemolytic Activity | [Ref:8306981]Lack hemolytic activity against rabbit red blood cells |
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| Cytotoxicity | [Ref.8306981]No cytotoxicity information found##[Ref.1438301]No cytotoxicity information found##[Ref.7842473]No cytotoxicity information found##[Ref.8565049]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P31107, P80283 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8306981, 1438301, 7842473, 8565049 |
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