Basic Information

IDDRAMP01673
SequenceGLWSKIKETGKEAAKAAGKAALNKIAEAV
Length29
NameDermaseptin-1 (DStar 01; Frogs, amphibians, animals)
SourcePhyllomedusa tarsius (Brownbelly leaf frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Swiss_Prot Entry P84921]Gram-positive bacteria: Staphylococcus aureus, Enterococcus faecalis;##Gram-neagtive bacterium: Pseudomonas aeruginosa.;##Fungi: Candida albicans and Paracoccidioides brasiliensis.
Hemolytic Activity[Ref:PubMed ID is not available]40% hemolytic activity at 128 µg/ml
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84921
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available

Physicochemical Properties

Residues29
SequenceGLWSKIKETGKEAAKAAGKAALNKIAEAV
Molecular Weight2954.423
Grand Average of Hydropathy-0.2
Isoelectric Point9.701
Charge at pH 7.42.546
Secondary StructureHelix: 0.207, Turn: 0.172, Sheet: 0.448
Instability Index8.421
Aromaticity0.034

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.