| ID | DRAMP00385 |
|---|---|
| Sequence | QLPICGETCVLGGCYTPNCRCQYPICVR |
| Length | 28 |
| Name | Panitide L2 (plants) |
| Source | Panicum laxum |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.5 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | [Ref.23195955] IC50 = 6.0 μM against HeLa cells. |
| N-terminal Modification | Pyroglutamyl modification |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23195955 |
Physicochemical Properties
| Residues | 28 |
|---|---|
| Sequence | QLPICGETCVLGGCYTPNCRCQYPICVR |
| Molecular Weight | 3090.665 |
| Grand Average of Hydropathy | 0.25 |
| Isoelectric Point | 7.773 |
| Charge at pH 7.4 | 0.406 |
| Secondary Structure | Helix: 0.286, Turn: 0.250, Sheet: 0.107 |
| Instability Index | 7.811 |
| Aromaticity | 0.071 |