Basic Information
| ID | DRAMP00797 |
|---|
| Sequence | GLPTCGETCTLGTCYVPDCSCSWPICMKN |
|---|
| Length | 29 |
|---|
| Name | Cliotide T3 (cT3; Plant defensin) |
|---|
| Source | Clitoria ternatea (Butterfly pea) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer |
|---|
| Pathogen | [Ref.21596752]Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC>100 µM), Pseudomonas aeruginosa ATCC 39018 (MIC>100 µM), Klebsiella pneumonia ATCC 13883 (MIC>100 µM). |
|---|
| Hemolytic Activity | [Ref:21596752] HD50=13.1 µM against human type A erythrocytes |
|---|
| Cytotoxicity | [Ref.21596752] Cytotoxicity: HeLa Cells (IC50=2.0 µM). |
|---|
| N-terminal Modification | No specific N-terminal |
|---|
| C-terminal Modification | No specific C-terminal |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 21596752 |
|---|
