Basic Information
| ID | DRAMP00796 |
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| Sequence | GEFLKCGESCVQGECYTPGCSCDWPICKKN |
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| Length | 30 |
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| Name | Cliotide T2 (cT2; Plant defensin) |
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| Source | Clitoria ternatea (Butterfly pea) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer |
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| Pathogen | [Ref.21596752]Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC>100 µM), Pseudomonas aeruginosa ATCC 39018 (MIC>100 µM), Klebsiella pneumonia ATCC 13883 (MIC>100 µM). |
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| Hemolytic Activity | [Ref:21596752] HD50>100 µM against human type A erythrocytes |
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| Cytotoxicity | [Ref.21596752] Cytotoxicity: HeLa Cells (IC50=8.0 µM). |
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| N-terminal Modification | No specific N-terminal |
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| C-terminal Modification | No specific C-terminal |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21596752 |
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