Basic Information
| ID | DRAMP00769 |
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| Sequence | GASCGETCFTGICFTAGCSCNPWPTCTRN |
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| Length | 29 |
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| Name | ChaC4 (Chassatide C4; Plant defensin) |
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| Source | Chassalia chartacea |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer |
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| Pathogen | Gram-negative bacterium: Escherichia coli (MIC>80 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 µM), Staphylococcus epidermidis (MIC>80 µM). |
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| Hemolytic Activity | [Ref.22467870] HD50=51.9 µM against human type A red blood cells. |
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| Cytotoxicity | [Ref.22467870] Cytotoxicity: HeLa cells (IC50=9.8 µM). |
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| N-terminal Modification | No specific N-terminal |
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| C-terminal Modification | No specific C-terminal |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22467870 |
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