Basic Information

IDDRAMP01082
SequenceILGKLLSTAAGLLSNL
Length16
NameAlyteserin-2a (toads, amphibians, animals)
SourceAlytes obstetricans (European midwife toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Cytotoxicity
Pathogen[Ref.19463738]Gram-positive bacterium: Staphylococcus aureus (MIC=50 µM).
Hemolytic Activity[Ref:19463738] LC50 = 135 μM against human erthrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal Modificationα-Amidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19463738

Physicochemical Properties

Residues16
SequenceILGKLLSTAAGLLSNL
Molecular Weight1583.91
Grand Average of Hydropathy1.275
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.438, Turn: 0.312, Sheet: 0.500
Instability Index10.8
Aromaticity0

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