Basic Information
| ID | DRAMP01167 |
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| Sequence | GILDAIKAIAKAAG |
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| Length | 14 |
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| Name | Hylaseptin-P1 (HSP1) |
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| Source | Hyla punctata (Polka-dot tree frog) (Spotted tree frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.14715660]Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.1-8.0 µg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa ATCC 27853 (MIC=48.8-64.0 µg/ml), Escherichia coli ATCC 25922 (MIC=24.4-32.0 µg/ml). |
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| Hemolytic Activity | [Ref.14715660] HSP1 MIC concentration (256 μg/mL = 195.2 μM) produced 4.7% hemolysis against human erythrocytes. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | [Ref.11297740] Free / [Ref.32828849] Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P84292 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 14715660, 32828849 |
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