Basic Information

IDDRAMP01184
SequenceGVLDILKGAAKDLAGHVATKVI
Length22
NameSPX(1-22)(truncated peptide of Syphaxin; Frogs, amphibians, animals)
SourceLeptodactylus syphax (Burgundy thin-toed frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 29213 (MIC=14.6 µM);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=40.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17628627]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17628627

Physicochemical Properties

Residues22
SequenceGVLDILKGAAKDLAGHVATKVI
Molecular Weight2189.597
Grand Average of Hydropathy0.745
Isoelectric Point8.505
Charge at pH 7.40.587
Secondary StructureHelix: 0.364, Turn: 0.136, Sheet: 0.318
Instability Index2.864
Aromaticity0

Similar Structure Search

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