Basic Information

IDDRAMP03587
SequenceSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV
Length47
NameDCD-1 (chain of Dermcidin; Human, mammals, animals)
SourceHomo sapiens (Human)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Proteolytic
PathogenGram-negative bacteria: Escherichia coli, Enterococcus faecalis;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P81605, A5JHP2, A5JHP3, P58461, Q53YJ2
PDB 2KSG ##2YMK resolved by X-ray.
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11694882, 17448443, 20510021

Physicochemical Properties

Residues47
SequenceSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV
Molecular Weight4705.279
Grand Average of Hydropathy-0.111
Isoelectric Point5.074
Charge at pH 7.4-2.722
Secondary StructureHelix: 0.298, Turn: 0.255, Sheet: 0.298
Instability Index10.128
Aromaticity0

Similar Structure Search

Candidates based on structure

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