| ID | dbAMP11247 |
|---|---|
| Sequence | SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL |
| Length | 48 |
| Name | Homo sapiens&&Dermcidin, DCD-1L&&DCD_HUMAN |
| Source | Homo sapiens |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus Newman (IC90=9.5±3µg/ml)&&Staphylococcus aureus ATCC 25923 (LD50=4µg/ml)&&Staphylococcus aureus 113 (IC90=12.5±2.1µg/ml)&&Staphylococcus aureus 113 (60-70% Killing=10.3µM)&&Staphylococcus aureus 113 (50-60% Killing=10.3µM)&&Staphyloc |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P81605 |
| PDB | 2YMK&&2KSG&&2KSG |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 21269460, 15340161, 20510021, 17448443, 19608861, 15489334, 23426625 |
Physicochemical Properties
| Residues | 48 |
|---|---|
| Sequence | SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL |
| Molecular Weight | 4818.436 |
| Grand Average of Hydropathy | -0.029 |
| Isoelectric Point | 5.074 |
| Charge at pH 7.4 | -2.722 |
| Secondary Structure | Helix: 0.312, Turn: 0.250, Sheet: 0.312 |
| Instability Index | 10.125 |
| Aromaticity | 0 |