Basic Information

IDDRAMP01189
SequenceATNIPFKVHFRCKAAFC
Length17
NameAndersonin-W1 (Frogs, amphibians, animals)
SourceOdorrana andersonii (Golden crossband frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=23.5 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC>47 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>47 µg/ml);##Yeast: Candida albicans ATCC 2002 (MIC=47 µg/ml).
Hemolytic Activity[Ref:22029824] It has no hemolytic activity against human red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys12 and Cys17)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues17
SequenceATNIPFKVHFRCKAAFC
Molecular Weight1953.336
Grand Average of Hydropathy0.365
Isoelectric Point9.505
Charge at pH 7.42.59
Secondary StructureHelix: 0.294, Turn: 0.118, Sheet: 0.176
Instability Index16.118
Aromaticity0.176

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