Basic Information

IDDRAMP01194
SequenceTSRCIFYRRKKCS
Length13
NameAndersonin-C1 (Frogs, amphibians, animals)
SourceOdorrana andersonii (Golden crossband frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=30 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>120 µg/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30 µg/ml).
Hemolytic Activity[Ref:22029824] It has 15.2±2.1% hemolytic activity at 50μg/ml against human red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues13
SequenceTSRCIFYRRKKCS
Molecular Weight1647.966
Grand Average of Hydropathy-0.969
Isoelectric Point10.321
Charge at pH 7.44.152
Secondary StructureHelix: 0.231, Turn: 0.154, Sheet: 0.000
Instability Index80.178
Aromaticity0.154

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