Basic Information

IDDRAMP01368
SequenceGFVDFLKKVAGTIANVVT
Length18
NameMaculatin-2.1 (Frogs, amphibians, animals)
SourceLitoria genimaculata (brown-spotted treefrog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus (MIC=100 µg/ml), Micrococcus luteus (MIC=100 µg/ml), Staphylococcus aureus (MIC=100 µg/ml), Staphylococcus epidermidis (MIC=50 µg/ml), Streptococcus uberis (MIC=25 µg/ml). (Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.15203252]No cytotoxicity information found##[Ref.9620615]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82068
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9620615, 15203252

Physicochemical Properties

Residues18
SequenceGFVDFLKKVAGTIANVVT
Molecular Weight1879.203
Grand Average of Hydropathy0.961
Isoelectric Point8.591
Charge at pH 7.40.553
Secondary StructureHelix: 0.444, Turn: 0.167, Sheet: 0.167
Instability Index-21.961
Aromaticity0.111

Similar Structure Search

Candidates based on structure

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