Basic Information

IDDRAMP01533
SequenceCVISAGWNHKIRCKLTGNC
Length19
NameNigroain-B1 (Frogs, amphibians, animals)
SourceRana nigrovittata (Black-striped frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.69 µg/ml), S. aureus ATCC43300 (MIC=50.00 µg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa PA01 (MIC=25.00 µg/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25.00 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.19778602]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys13 and Cys19)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19778602

Physicochemical Properties

Residues19
SequenceCVISAGWNHKIRCKLTGNC
Molecular Weight2103.494
Grand Average of Hydropathy0.032
Isoelectric Point9.158
Charge at pH 7.42.516
Secondary StructureHelix: 0.263, Turn: 0.263, Sheet: 0.105
Instability Index11.568
Aromaticity0.053

Similar Structure Search

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