Basic Information

IDDRAMP01721
SequenceHFLGKLVNLAKKIL
Length14
Name[T5k]temporin-DRa (Frogs, amphibians, animals)
SourceRana draytonii
ActivityAntimicrobial, Antibacterial
PathogenClinical isolates: Propionibacterium acnes strain ATCC 11828 (MIC=6 µM), P. acnes strain 32548 (MIC=6 µM), P. acnes strain 33257 (MIC=12.5 µM), P. acnes strain 50247 (MIC=3 µM), P. acnes strain 18380 (MIC=12.5 µM), P. acnes strain 15725 (MIC=6 µM), P. acnes strain 29903 (MIC=12.5 µM), P. acnes strain 31766 (MIC=3 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.22374306]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22374306

Physicochemical Properties

Residues14
SequenceHFLGKLVNLAKKIL
Molecular Weight1593.996
Grand Average of Hydropathy0.693
Isoelectric Point10.302
Charge at pH 7.42.587
Secondary StructureHelix: 0.500, Turn: 0.143, Sheet: 0.357
Instability Index-2.557
Aromaticity0.071

Similar Structure Search

Candidates based on structure

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