Basic Information

IDDRAMP20832
SequenceIDWKKLLNAAKQIL
Length14
NamePolybia-MP1S-D8N
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.29075946] Gram-positive bacteria: Bacillus subtilis (MIC=0.8μM), Staphylococcus aureus (MIC=0.8μM), Staphylococcus epidermidis (MIC=37.5μM);##Gram-negative bacteria:Escherichia coli (MIC=50μM), Shigella dysenteriae (MIC=100μM), Klebsiella pneumoniae (MIC=37.5μM)
Hemolytic Activity[Ref.29075946] 16.3% hemolysis at 12.5μM, 37.8% hemolysis at 25μM against human red cells
Cytotoxicity[Ref.29075946] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29075946

Physicochemical Properties

Residues14
SequenceIDWKKLLNAAKQIL
Molecular Weight1654.005
Grand Average of Hydropathy0.064
Isoelectric Point9.703
Charge at pH 7.41.55
Secondary StructureHelix: 0.429, Turn: 0.071, Sheet: 0.357
Instability Index33.864
Aromaticity0.071

Similar Structure Search

Candidates based on structure

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