| ID | DRAMP20940 |
|---|---|
| Sequence | IDWKKLLDAAKKIL |
| Length | 14 |
| Name | Polybia-MP1S-Q12K |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | [Ref.29075946] Gram-positive bacteria: Bacillus subtilis (MIC=0.8 μM), Staphylococcus aureus (MIC=1.2 μM), Staphylococcus epidermidis (MIC=50 μM) |
| Hemolytic Activity | [Ref.29075946]9.6% hemolysis at 12.5μM,13.9% hemolysis at 25μM against human red blood cells |
| Cytotoxicity | [Ref.29075946] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 29075946 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | IDWKKLLDAAKKIL |
| Molecular Weight | 1655.033 |
| Grand Average of Hydropathy | 0.036 |
| Isoelectric Point | 9.528 |
| Charge at pH 7.4 | 1.548 |
| Secondary Structure | Helix: 0.429, Turn: 0.000, Sheet: 0.357 |
| Instability Index | 10.914 |
| Aromaticity | 0.071 |