Basic Information

IDDRAMP01738
SequenceFFPIVGKLLS
Length10
NameTemporin-ALk (Frogs, amphibians, animals)
SourceAmolops loloensis
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.19843479]Gram-positive bacterium: Staphylococcus aureus ATCC2592 (MIC=15 µg/mL);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=30 µg/mL), Bacillus dysenteriae (MIC=60 µg/mL), Acinetobacter calcoaceticus (MIC=75 µg/mL), Psecdomonas aeruginosa (MIC=25 µg/mL);##Yeast: Candida albicans ATCC2002 (MIC=15 µg/mL).
Hemolytic Activity[Ref:19843479]25% hemolytic activity at 100 μg/mL against rabbit red blood cells.
Cytotoxicity[Ref.19843479]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19843479

Physicochemical Properties

Residues10
SequenceFFPIVGKLLS
Molecular Weight1120.383
Grand Average of Hydropathy1.52
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.600, Turn: 0.300, Sheet: 0.200
Instability Index-5.7
Aromaticity0.2

Similar Structure Search

Candidates based on structure

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