Basic Information

IDDRAMP02819
SequenceGLLKRIKTLL
Length10
NameAnoplin (Insects, arthropods, invertebrates, animals)
SourceAnoplius samariensis (Solitary wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.29614317]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=26 μg/mL);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=13 μg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=19.5 μg/mL).##[Ref.25316570]Gram-positive bacteria : Staphylococcus aureus (MIC=64 μg/ml), bacillus subtilis (MIC=32 μg/ml);##Gram-negative bacteria : Escherichia coli (MIC=64 μg/ml), Peudomonas eruginosa (MIC=32 μg/ml).##[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=200 μg/ml), Bacillus subtilis DELTA (MIC=300 μg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=200 μg/ml), Pseudomonas aeruginosa PAO (MIC=100 μg/ml), Zymomonas mobilis 10988 (MIC=40 μg/ml);##Fungi : Candida parapsilosis (MIC=15 μg/ml)
Hemolytic Activity[Ref.25316570] 1% hemolysis at 12.5 μg/ml , 2% hemolysis at 25 μg/ml , 1% hemolysis at 50 μg/ml , 1.5% hemolysis at 100 μg/ml , 1.5% hemolysis at 200 μg/ml against mice red blood cells.##[Ref.27862650]3% hemolysis at 100μg/ml , 6% hemolysis at 200μg/ml , 10% hemolysis at 300μg/ml , 12% hemolysis at 500μg/ml against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C005
PDB 2MJQ,2MJR,2MJS,2MJT
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29614317, 25316570#27862650

Physicochemical Properties

Residues10
SequenceGLLKRIKTLL
Molecular Weight1154.489
Grand Average of Hydropathy0.63
Isoelectric Point11.166
Charge at pH 7.42.552
Secondary StructureHelix: 0.500, Turn: 0.100, Sheet: 0.400
Instability Index24.62
Aromaticity0

Similar Structure Search

Candidates based on structure

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