ABPDB

Basic Information

ID	DRAMP20811
Sequence	RLKKIGKVLKWI
Length	12
Name	RI12 (PMAP-36 peptide derivative)
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen	[Ref.27251456] Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=64 μM, MBC=128 μM), Staphylococcus aureus 25923 (MIC=128 μM, MBC=128 μM), Staphylococcus epidermidis 12228 (MIC=64 μM, MBC=64 μM), Bacillus subtilis 63501 (MIC=2 μM, MBC=8 μM);##Gram-negative bacteria: Escherichia coli 25922 (MIC=8 μM, MBC=32 μM), Escherichia coli EC183 (MIC=2 μM, MBC=4 μM), Escherichia coli 1005 (MIC=16 μM, MBC=32 μM), Salmonella typhimurium C77-31 (MIC=8 μM, MBC=32 μM);##Fungi: Candida albicans 2.2086 (MIC=128 μM, MFC=128 μM), Candida albicans CA276 (MIC=128 μM, MFC=128 μM), Candida tropicalis 2.1975 (MIC=8 μM, MFC=8 μM), Candida krusei 2.1857 (MIC=16 μM, MFC=16 μM).
Hemolytic Activity	[Ref.27251456] Non-hemolysis upto 128 μM, MHC>128 μM against human red blood cells.
Cytotoxicity	[Ref.27251456] No cytotoxicity information found
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	27251456

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.