Basic Information

IDDRAMP01967
SequenceFLPIIAGAAAKVVQKIFCAISKKC
Length24
NameBrevinin-1Yb (Frogs, amphibians, animals)
SourceLithobates yavapaiensis (North America leopard frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=3 μM);##Gram-negative bacteria : Escherichia coli(MIC=25 μM);##Fungi : Candida albicans(MIC=3 μM)
Hemolytic Activity[Ref.19254736] LC50=16 μM against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19254736

Physicochemical Properties

Residues24
SequenceFLPIIAGAAAKVVQKIFCAISKKC
Molecular Weight2520.15
Grand Average of Hydropathy1.163
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.375, Turn: 0.125, Sheet: 0.250
Instability Index6.996
Aromaticity0.083

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