Basic Information
| ID | DRAMP02273 |
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| Sequence | KIAKVALKAL |
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| Length | 10 |
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| Name | PGLa-H (chain of PYLa/PGLa A; Frogs, amphibians, animals) |
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| Source | Xenopus laevis (African clawed frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.22014884]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=8.7 µg/ml), Bacillus subtilis (MIC=14.4 µg/ml), Staphylococcus aureus (MRSA) (MIC=67.8 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=23.6 µg/ml) |
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| Hemolytic Activity | [Ref.22014884]3.15% hemolytic activity at 100 μg/mL, 7.95% hemolytic activity at 200 μg/mL against rabbit red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q99134, B7ZSG6, Q91826 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22014884, 1717472 |
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