Basic Information

IDDRAMP02308
SequenceIIGHLIKTALGMLGL
Length15
NameSigniferin-2.1 (Frogs, amphibians, animals)
SourceCrinia signifera (Common eastern froglet)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus (MIC=25 µM), Enterococcus faecalis ATCC 29212 (MIC=100 µM), Leuconostoc lactis (MIC=12 µM), Listeria innocua (MIC=50 µM), Micrococcus luteus ATCC 9341 (MIC=25 µM), Staphylococcus aureus ATCC 29213 (MIC=12 µM), Staphylococcus epidermidis ATCC14990 (MIC=25 µM), Streptococcus uberis (MIC=25 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P86131
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15317042, 16470724, 18601958

Physicochemical Properties

Residues15
SequenceIIGHLIKTALGMLGL
Molecular Weight1549.962
Grand Average of Hydropathy1.56
Isoelectric Point8.757
Charge at pH 7.40.592
Secondary StructureHelix: 0.467, Turn: 0.200, Sheet: 0.400
Instability Index3.673
Aromaticity0

Similar Structure Search

Candidates based on structure

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