Basic Information

IDDRAMP02320
SequenceFIGGIISFIKKLF
Length13
NameGrammistin PpIIb (Group II grammistin; fish, chordates, animals)
SourcePogonoperca punctata (Clown grouper) (Bearded grouper)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.Fish. Sci. 2001 Feb;67:163-169.]Gram-positive bacteria: Bacillus subtilis IAM 1026 (MIC=6.25 µg/ml), Staphylococcus aureus IAM 1011 (MIC=3.13 µg/ml);##Gram-negative bacteria: Aeromonas salmonicida NCIBM 1102 (MIC>50 µg/ml), Escherichia coli JCM 1649 (MIC=50 µg/ml), P. dameselae subsp. Piscicida Sp 9587 (MIC=12.5 µg/ml), Salmonella typhimurium S1 (MIC>50 µg/ml), S. putrefaciens IAM 1509 (MIC=6.25 µg/ml), Vibrio anguillarum NCIBM 829 (MIC=12.5 µg/ml), Vibrio parahaemolyticus (MIC=25 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P69844
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available

Physicochemical Properties

Residues13
SequenceFIGGIISFIKKLF
Molecular Weight1482.849
Grand Average of Hydropathy1.6
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.615, Turn: 0.231, Sheet: 0.077
Instability Index-0.869
Aromaticity0.231

Similar Structure Search

Candidates based on structure

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