Basic Information

IDDRAMP02660
SequenceRRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR
Length33
NameNeutrophil defensin 4 (RMAD-4; primates, mammals, animals)
SourceMacaca mulatta (Rhesus monkey)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82319
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues33
SequenceRRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR
Molecular Weight3964.598
Grand Average of Hydropathy-0.642
Isoelectric Point10.603
Charge at pH 7.47.409
Secondary StructureHelix: 0.212, Turn: 0.273, Sheet: 0.061
Instability Index68.888
Aromaticity0.121

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.