Basic Information

IDDRAMP02698
SequenceRRTCHCRSRCLRRESNSGSCNINGRIFSLCCR
Length32
NameRhesus macaque oral alpha-defensins (ROADs; primates, mammals, animals)
SourceMacaca mulatta (Rhesus monkey)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Fungi: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot B5AKV3
PDB 2K1I
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18930922

Physicochemical Properties

Residues32
SequenceRRTCHCRSRCLRRESNSGSCNINGRIFSLCCR
Molecular Weight3745.317
Grand Average of Hydropathy-0.759
Isoelectric Point10.437
Charge at pH 7.46.448
Secondary StructureHelix: 0.156, Turn: 0.312, Sheet: 0.094
Instability Index112.703
Aromaticity0.031

Similar Structure Search

Candidates based on structure

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