Basic Information

IDDRAMP02662
SequenceRRTCRCRFGRCFRRESYSGSCNINGRISSLCCR
Length33
NameNeutrophil defensin 6 (RMAD-6; primates, mammals, animals)
SourceMacaca mulatta (Rhesus monkey)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82320
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues33
SequenceRRTCRCRFGRCFRRESYSGSCNINGRISSLCCR
Molecular Weight3904.501
Grand Average of Hydropathy-0.752
Isoelectric Point10.603
Charge at pH 7.47.409
Secondary StructureHelix: 0.182, Turn: 0.303, Sheet: 0.061
Instability Index74.724
Aromaticity0.091

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