Basic Information

IDDRAMP02661
SequenceRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR
Length32
NameNeutrophil defensin 5 (RMAD-5; primates, mammals, animals)
SourceMacaca mulatta (Rhesus monkey)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82319
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues32
SequenceRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR
Molecular Weight3808.412
Grand Average of Hydropathy-0.522
Isoelectric Point9.984
Charge at pH 7.46.409
Secondary StructureHelix: 0.219, Turn: 0.281, Sheet: 0.062
Instability Index52.828
Aromaticity0.125

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