Basic Information

IDDRAMP02780
SequenceVTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
Length43
NameDefensin-B (Defensin B; Insects, animals)
SourceAnomala cuprea (Cupreous chafer beetle)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus megaterium (MIC=1.2-2.5 µM), Bacillus subtilis (MIC=20-40 µM), Micrococcus luteus (MIC=1.2-2.5 µM), Staphylococcus aureus (MIC=2.5-5 µM);##Gram-negative bacterium: X. japonicus (MIC=20-40 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P83668
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11719071

Physicochemical Properties

Residues43
SequenceVTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
Molecular Weight4438.148
Grand Average of Hydropathy0.467
Isoelectric Point8.34
Charge at pH 7.41.446
Secondary StructureHelix: 0.256, Turn: 0.233, Sheet: 0.233
Instability Index17.809
Aromaticity0.047

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