Basic Information

IDDRAMP03119
SequenceATCDLASFSSQWVTPNDSLCAAHCIARRYRGGYCNGKRVCVCR
Length43
NameDef-BAT (hybrid defensins; Insects, animals)
SourceAnopheles gambiae (African malaria mosquito)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Staphylococcus aureus strain 21 (IC90=6.25 µg/mL), Staphylococcus aureus strain 4 (IC90=6.25 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q17027
PDB 2E3F
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18214975

Physicochemical Properties

Residues43
SequenceATCDLASFSSQWVTPNDSLCAAHCIARRYRGGYCNGKRVCVCR
Molecular Weight4740.394
Grand Average of Hydropathy-0.151
Isoelectric Point8.942
Charge at pH 7.43.491
Secondary StructureHelix: 0.233, Turn: 0.233, Sheet: 0.163
Instability Index28.674
Aromaticity0.093

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