Basic Information

IDDRAMP20882
SequenceATCDLLSASTPWGSLNHSACAAHCLTKRYKGGRCRNGICRCRR
Length43
NameLOUDEF1
SourceHuman body louse (Pediculhumanus humanus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.29501691] Gram-positive bacteria: Staphylococcus aureus (MIC=35μ±μ1.3 μg/mL), Bacillus subtilis (MIC=7μ±μ1.6 μg/mL);##Fungi: Candida albicans (MIC= 19.1μ±μ9.6 μg/mL)
Hemolytic Activity[Ref.29501691] 0% haemolysis at 10 μg/ml, 0% haemolysis at 25 μg/ml, 0% haemolysis at 50 μg/ml, 0% haemolysis at 100 μg/ml, 0% haemolysis at 200 μg/ml against sheep red blood cells
Cytotoxicity[Ref.29501691] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot E0VPU4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29501691

Physicochemical Properties

Residues43
SequenceATCDLLSASTPWGSLNHSACAAHCLTKRYKGGRCRNGICRCRR
Molecular Weight4695.405
Grand Average of Hydropathy-0.435
Isoelectric Point9.693
Charge at pH 7.46.527
Secondary StructureHelix: 0.163, Turn: 0.256, Sheet: 0.209
Instability Index41.333
Aromaticity0.047

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