| ID | DRAMP02854 |
|---|---|
| Sequence | GGLRSLGRKILRAWKKYGPIIVPIIRIG |
| Length | 28 |
| Name | Cathelicidin-5 (Antibacterial peptide BMAP-28; Myeloid antib |
| Source | Bos taurus (Bovine) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 µM), E. coli ML35 (MIC=2 µM), E. coli D21 (MIC=0.5 µM), Salmonella typhimurium ATCC 14028 (MIC=1 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=1 µM), Serratia marcescens ATCC 8100 (MIC=2 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 µM), Staphylococcus aureus Cowan 1 (MIC=1 µM), Staphylococcus aureus (MRSA) (MIC=4 µM), Staphylococcus epidermidis ATCC 12228 (MIC=1 µM), Bacillus megaterium Bm11 (MIC=2 µM).##Fungi: Candida albicans (MIC=8 µM), Cryptococcus neoformans (MIC=4 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P54229, A5PJ96, B9UKL6 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8910461, 8706679 |
Physicochemical Properties
| Residues | 28 |
|---|---|
| Sequence | GGLRSLGRKILRAWKKYGPIIVPIIRIG |
| Molecular Weight | 3131.85 |
| Grand Average of Hydropathy | 0.232 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 6.547 |
| Secondary Structure | Helix: 0.429, Turn: 0.286, Sheet: 0.143 |
| Instability Index | 48.161 |
| Aromaticity | 0.071 |