Basic Information
| ID | DRAMP01513 |
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| Sequence | GIFSKLGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC |
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| Length | 46 |
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| Name | Esculentin-1 (Frogs, amphibians, animals) |
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| Source | Rana esculenta (Edible frog) (Pelophylax esculentus) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacteria: Escherichia coli D21 (MIC=0.2 µM), Pseudomonas aeruginosaATCC15692 (MIC=0.7 µM);##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.1 µM), Staphylococcus aureus Cowan1 (MIC=0.4 µM).##Fungi: Candida albicans (MIC=0.5 µM), Saccharomyces cerevisiae (MIC=0.9 µM). |
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| Hemolytic Activity | [Ref. 8163497] LC>100μM |
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| Cytotoxicity | [Ref.8508915]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys40 and Cys46) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P32414 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8508915 |
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