Basic Information
| ID | DRAMP01491 |
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| Sequence | GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC |
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| Length | 46 |
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| Name | Esculentin-1B (Frogs, amphibians, animals) |
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| Source | Rana esculenta (European Edible frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-negative bacteria: Escherichia coli D21 (MIC=0.2 µM), Pseudomonas aeruginosa ATCC15692 (MIC=0.7 µM);##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.1 µM), Staphylococcus aureus cowan I (MIC=0.4 µM).##Fungi: Candida albicans (MIC=0.5 µM), Saccharomyces cerevisiae (MIC=0.9 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.8163497]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys40 and Cys46) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P40844 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8163497 |
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