Basic Information
| ID | DRAMP01483 |
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| Sequence | RIFSKIGGKAIKNLILKGIKNIGKEVGMDVIRTGIDVAGCKIKGEC |
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| Length | 46 |
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| Name | Esculentin-1ISb (Frogs, amphibians, animals) |
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| Source | Odorrana ishikawae (Japanese Endangered frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacterium: Escherichia coli (MC=3.1 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 µM), Staphylococcus aureus (MRSA) (MIC=12.5 µM), Bacillus subtilis (MIC=12.5 µM).##Yeast: Candida albicans (MIC=50 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys40 and Cys46) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21193000 |
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