Basic Information

IDDRAMP01514
SequenceGIFSKFGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
Length46
NameEsculentin-1 (Frogs, amphibians, animals)
SourcePelophylax saharicus (Sahara frog) (Rana saharica)
ActivityAntimicrobial, Antibacterial
PathogenNo MICs found in DRAMP database
Hemolytic Activity[Ref.8163497] MHC>100 µM against human red blood cell.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys40 and Cys46)
Linear/Cyclic/BranchedCyclic
Uniprot P84840
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16394170

Physicochemical Properties

Residues46
SequenceGIFSKFGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
Molecular Weight4921.892
Grand Average of Hydropathy0.061
Isoelectric Point9.834
Charge at pH 7.45.491
Secondary StructureHelix: 0.326, Turn: 0.261, Sheet: 0.152
Instability Index-4.452
Aromaticity0.043

Similar Structure Search

Candidates based on structure

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