Basic Information

IDDRAMP02984
SequenceGLRKKFRKTRKRIQKLGRKIGKTGRKVWKAWREYGQIPYPCRI
Length43
NameNeutrophil cationic antibacterial polypeptide of 11 kDa (CAP11; pigs, mammals, animals)
SourceCavia porcellus (Domestic guinea pig)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (ED50=30-35 nM);##Gram-positive bacterium: Staphylococcus aureus (ED50=90-120 nM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q91X12
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8644997

Physicochemical Properties

Residues43
SequenceGLRKKFRKTRKRIQKLGRKIGKTGRKVWKAWREYGQIPYPCRI
Molecular Weight5286.356
Grand Average of Hydropathy-1.295
Isoelectric Point11.816
Charge at pH 7.415.506
Secondary StructureHelix: 0.279, Turn: 0.163, Sheet: 0.093
Instability Index10.428
Aromaticity0.116

Similar Structure Search

Candidates based on structure

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