Basic Information

IDDRAMP03797
SequenceGLRKRLRKFRNKIKEKLKKIGQKIQGFVPKLAPRTDY
Length37
NameCAP7 (C-terminal fragment of CAP18; lagomorphs, mammals, animals)
SourceOryctolagus cuniculus (Rabbit)
ActivityAntimicrobial, Antibacterial
Pathogen[No NaCl]: Escherichia coli DH5a (MIC=0.19 µM), Escherichia coli ML-35p (MIC=0.05 µM), Pseudomonas aeruginosa PAO1 (MIC=0.2 µM), Pseudomonas aeruginosa MR3007 (MIC=0.05 µM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=1.24 µM), Staphylococcus aureus 93918 (MIC=0.41 µM).##[100 mM NaCl]: Escherichia coli DH5a (MIC=0.21 µM), Escherichia coli ML-35p (MIC=0.09 µM), Pseudomonas aeruginosa PAO1 (MIC=0.62 µM), Pseudomonas aeruginosa MR3007 (MIC=0.36 µM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=1.36 µM), Staphylococcus aureus 93918 (MIC=0.63 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P25230
PDB 1LYP
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8132348, 10768969, 7649303

Physicochemical Properties

Residues37
SequenceGLRKRLRKFRNKIKEKLKKIGQKIQGFVPKLAPRTDY
Molecular Weight4453.378
Grand Average of Hydropathy-1.114
Isoelectric Point11.538
Charge at pH 7.411.534
Secondary StructureHelix: 0.297, Turn: 0.162, Sheet: 0.162
Instability Index30.997
Aromaticity0.081

Similar Structure Search

Candidates based on structure

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